Spironolactone

Overview

Spironolactone is a potassium-sparing diuretic that is used to reduce fluid retention and treat high blood pressure. It works as an aldosterone antagonist, blocking the effect of aldosterone and aiding in the excretion of sodium and water from the body.

API suppliers (16)

Suppliers of Spironolactone backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• TIANJIN TIANYAO PHARMACEUTICALS CO LTDChina2 active DMF
• Gedeon RichterHungary1 active DMF
• EUROAPI FRANCEFrance1 active DMF
• Gedeon RichterHungary1 active DMF
• EUROAPI FRANCEFrance1 active DMF
• Zhejiang Hisun Pharmaceutical Co., Ltd.China1 active DMF
• HUBEI GOTO BIOTECHNOLOGY CO LTD1 active DMF
• EUROAPI FRANCEFrance1 active DMF
• Zhejiang Hisun Pharmaceutical Co., Ltd.China1 active DMF
• ANTIBIOTICOS SPA
• Piramal Healthcare UK Ltd.United Kingdom
• MEDIMPEX NORTHAMERICA INC
• SCHERING AG
• OLON SPAItaly
• Dipharma Francis SrlItaly
• ZHEJIANG XINHUA PHARMACEUTICAL CO LTD

Patent & exclusivity (US)

Per the FDA Orange Book (36 approved US products), the latest listed US patent on Spironolactone expires 28 Oct 2036. Generic API sourcing typically opens up once these lapse.

Therapeutic areas