Macitentan
Overview
Macitentan is an endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It works by preventing the vasoconstriction and proliferation effects of endothelin-1, a potent vasoconstrictor.
API suppliers (13)
Suppliers of Macitentan evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 12 of 13 suppliers.
6 of 13 hold a GMP certificate on record in the EU or UK registers
- MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
- APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
- RAKS PHARMA PVT LTDIndia1 active DMF
- HONOUR LAB LTDIndia1 active DMF GMP on record
- TAPI NL BVNetherlands1 active DMF
- Zydus Lifesciences LimitedIndia1 active DMF GMP on record
- SEASONS BIOTECHNOLOGY (TAIZHOU) CO LTDChina1 active DMF
- Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
- Laurus Labs LimitedIndia1 active DMF GMP on record
- ZHEJIANG GUOBANG PHARMACEUTICAL CO LTD1 active DMF
- Zhejiang Huayi Pharmaceutical Co., Ltd.China1 active DMF
- Zhejiang Ausun Pharmaceutical Co., Ltd.China1 active DMF GMP on record
- ZHEJIANG XIANFENG TECHNOLOGY GROUP CO LTDChina1 active DMF
Patent & exclusivity (US)
Per the FDA Orange Book (13 approved US products), the latest listed US patent on Macitentan expires 18 Oct 2029 and exclusivity 28 Aug 2028. Generic API sourcing typically opens up once these lapse.
Therapeutic areas
Do you supply Macitentan? Get in front of buyers actively sourcing it.
We route real sourcing requests from pharma buyers to vetted, verified partners — qualified leads, not just a listing. Tell us what you make and we'll be in touch about becoming a Verified Supplier Partner.
Ready to Accelerate Your
Discovery Workflow?
Find, vet, and source drug-manufacturing partners faster — with FDA compliance screening built in. Start free for 7 days.