Tafamidis

Overview

Tafamidis is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2103837).

API suppliers (13)

Suppliers of Tafamidis evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• HUNAN OUYA PHARMACEUTICAL CO LTD1 active DMF
• MSN Laboratories Private LimitedIndia1 active DMF GMP on record
• SS PHARMA LLCIndia1 active DMF
• AURORE LIFE SCIENCES PRIVATE LTD1 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• BIOPHORE INDIA PHARMACEUTICALS PVT LTD1 active DMF
• Cipla USA, Inc.USA1 active DMF
• TAPI NL BVNetherlands1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• SAPTAGIR LABORATORIES PRIVATE LTDIndia1 active DMF
• FARMAK ASUkraine

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Tafamidis expires 31 Aug 2035 and exclusivity 3 May 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid

Canonical SMILES

C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl

InChIKey

TXEIIPDJKFWEEC-UHFFFAOYSA-N