Sildenafil

Overview

Sildenafil is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL192).

API suppliers (17)

Suppliers of Sildenafil backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• AMOLI ORGANICS PRIVATE LTD2 active DMF
• RAKS PHARMA PVT LTDIndia1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF
• MATRIX PHARMACORP PRIVATE LTD1 active DMF
• JBC Pharmaceuticals Ltd.United Kingdom1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF
• MATRIX PHARMACORP PRIVATE LTD1 active DMF
• Cadila Pharmaceuticals LimitedIndia1 active DMF
• MATRIX PHARMACORP PRIVATE LTD1 active DMF
• Cadila Pharmaceuticals LimitedIndia1 active DMF
• PH HEALTH LTD1 active DMF
• RAKS PHARMA PVT LTDIndia1 active DMF
• Macleods Pharmaceuticals Ltd.India1 active DMF
• JBC Pharmaceuticals Ltd.United Kingdom1 active DMF
• APITORIA PHARMA PRIVATE LTDIndia1 active DMF
• MYLAN LABORATORIES LTD
• SIGNA SA DE CV

Patent & exclusivity (US)

Per the FDA Orange Book (79 approved US products), the latest listed US patent on Sildenafil expires 16 Dec 2033 and exclusivity 31 Jan 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,5-d]pyrimidin-7-one

Canonical SMILES

CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C

InChIKey

BNRNXUUZRGQAQC-UHFFFAOYSA-N