Octreotide

Overview

Octreotide is a protein active pharmaceutical ingredient (ChEMBL CHEMBL1680).

API suppliers (8)

Suppliers of Octreotide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• Sun Pharmaceutical Industries LimitedIndia2 active DMF GMP on record
• SHILPA PHARMA LIFESCIENCES LTDIndia1 active DMF
• POLYPEPTIDE LABORATORIES INCUnited States1 active DMF GMP on record
• USV PRIVATE LTDIndia1 active DMF GMP on record
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• CHENGDU SHENGNUO BIOPHARM CO LTDChina1 active DMF
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• BACHEM AMERICAS INC

EU CEP holders (10)

Companies holding a valid EU Certificate of Suitability (CEP) for Octreotide, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (46 approved US products), the latest listed US patent on Octreotide expires 29 Dec 2041 and exclusivity 26 Jun 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

Canonical SMILES

C[C@H]([C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)[C@@H](CC5=CC=CC=C5)N)C(=O)N[C@H](CO)[C@@H](C)O)O

InChIKey

DEQANNDTNATYII-OULOTJBUSA-N