Octreotide

Overview

Octreotide is a protein active pharmaceutical ingredient (ChEMBL CHEMBL1680).

API suppliers (5)

Suppliers of Octreotide backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Sun Pharmaceutical Industries LimitedIndia2 active DMF
• POLYPEPTIDE LABORATORIES INCUnited States1 active DMF
• POLYPEPTIDE LABORATORIES INCUnited States1 active DMF
• USV PRIVATE LTD1 active DMF
• BACHEM AMERICAS INC

Patent & exclusivity (US)

Per the FDA Orange Book (46 approved US products), the latest listed US patent on Octreotide expires 29 Dec 2041 and exclusivity 25 Jun 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

Canonical SMILES

C[C@H]([C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)[C@@H](CC5=CC=CC=C5)N)C(=O)N[C@H](CO)[C@@H](C)O)O

InChIKey

DEQANNDTNATYII-OULOTJBUSA-N