Levodopa

Overview

Levodopa is a precursor to the neurotransmitter dopamine used to treat Parkinson's disease and dopamine-responsive dystonia. It is often combined with a peripheral decarboxylase inhibitor like carbidopa to increase its effectiveness.

API suppliers (15)

Suppliers of Levodopa evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• AJINOMOTO CO INCJapan2 active DMF GMP on record
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• Hetero Drugs LimitedIndia1 active DMF GMP on record
• ZHEJIANG YONGTAI CHIRAL MEDICINE TECHNOLOGY CO LTDChina1 active DMF
• MIANYANG SHENGSHI HEALTH TECHNOLOGY CO LTD1 active DMF
• MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
• Divis LaboratoriesIndia1 active DMF GMP on record
• SHANDONG XINHUA PHARMACEUTICAL CO LTDChina1 active DMF GMP on record
• Zhejiang Wild Wind Pharmaceutical Co.,Ltd.China1 active DMF
• Acella Pharmaceuticals, LLCUnited States1 active DMF
• MAITHRI DRUGS PRIVATE LTDIndia1 active DMF GMP on record
• PFC ITALIANA SRL DIV ALFA CHEMICALS ITALIANA
• EGIS PHARMACEUTICALS PRIVATE LTD GMP on record
• Torrent PharmaceuticalsIndia GMP on record
• KEY PHARMACEUTICALS INC SUB SCHERING PLOUGH CORP

EU CEP holders (10)

Companies holding a valid EU Certificate of Suitability (CEP) for Levodopa, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Levodopa expires 21 Oct 2033. Generic API sourcing typically opens up once these lapse.

Therapeutic areas