Letrozole

Overview

Letrozole is an oral non-steroidal aromatase inhibitor used in the treatment of hormonally-responsive breast cancer after surgery. It lowers estrogen levels in postmenopausal women, slowing the growth of certain types of breast tumors that are estrogen-dependent.

API suppliers (24)

Suppliers of Letrozole evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• TAPI NL BVNetherlands2 active DMF
• Natco PharmaIndia1 active DMF GMP on record
• Cipla USA, Inc.USA1 active DMF
• SCINOPHARM TAIWAN LTDTaiwan1 active DMF
• SYNTHIMED LABS PRIVATE LIMITEDIndia1 active DMF GMP on record
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• Hetero Labs LimitedIndia1 active DMF GMP on record
• SHILPA PHARMA LIFESCIENCES LTDIndia1 active DMF
• WANYANG HENGSHUI PHARMACEUTICAL CO LTDChina1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• DR REDDYS LABORATORIES LTD1 active DMF GMP on record
• Sichuan Xieli Pharmaceutical Co LtdChina
• Natco PharmaIndiaCEP GMP on record
• MAC CHEM PRODUCTS INDIA PVT LTD GMP on record
• MYLAN LABORATORIES LTD GMP on record
• JIANGSU HENGRUI PHARMACEUTICALS CO LTDChina GMP on record
• USV PRIVATE LTDIndia GMP on record
• Zhejiang Hisun Pharmaceutical Co., Ltd.China GMP on record
• SANMAR SPECIALITY CHEMICALS LTD
• TAI HENG INDUSTRY CO LTD
• FRESENIUS KABI ONCOLOGY LTDIndia GMP on record
• Fresenius Kabi AGGermanyCEP GMP on record
• Cadila Healthcare LimitedIndia
• Apotex Pharmachem India Pvt. Ltd.India

Chemical identity

IUPAC name

4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile

Canonical SMILES

C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3

InChIKey

HPJKCIUCZWXJDR-UHFFFAOYSA-N

Therapeutic areas