Iloperidone

Overview

Iloperidone is an atypical antipsychotic used for the treatment of schizophrenia. It operates as an antagonist for certain dopamine and serotonin receptors, helping manage symptoms of the disorder.

API suppliers (23)

Suppliers of Iloperidone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• W R GRACE AND CO -CONNUnited States2 active DMF
• Apex Healthcare LimitedIndia2 active DMF
• SWATI SPENTOSE PRIVATE LTDIndia2 active DMF
• MAHENDRA CHEMICALSIndia2 active DMF
• HARMAN FINOCHEM LTDIndia2 active DMF GMP on record
• PROCOS SPAItaly1 active DMF GMP on record
• SHIJIAZHUANG CANSAV PHARMACEUTICAL TECHNOLOGY CO LTDChina1 active DMF
• CAMBREX KARLSKOGA ABSweden1 active DMF GMP on record
• Formosa Laboratories, Inc.Taiwan1 active DMF GMP on record
• DELTA SYNTHETIC CO LTDTaiwan1 active DMF
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• Lupin LimitedIndia1 active DMF GMP on record
• Viyash Scientific LtdIndia1 active DMF GMP on record
• MOEHS IBERICA SLSpain1 active DMF GMP on record
• GUFIC BIOSCIENCES LTD GMP on record
• JENSEN-SALSBERY LABS DIV RICHARDSON-MERRILL INC
• SANOFI PHARMACEUTICALS INC
• NAPP CHEMICALS INC
• HOECHST AG
• SYN-TECH CHEM AND PHARM CO LTDTaiwan
• PROFARMACO SRL
• KONDUSKAR LABORATORIES PVT LTD
• MYLAN LABORATORIES LTD GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (102 approved US products), the latest listed US patent on Iloperidone expires 10 May 2031 and exclusivity 24 Sept 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide

Canonical SMILES

CCN(CC)CC(=O)NC1=C(C=CC=C1C)C

InChIKey

NNJVILVZKWQKPM-UHFFFAOYSA-N

Therapeutic areas