Iloperidone

Overview

Iloperidone is an atypical antipsychotic used for the treatment of schizophrenia. It operates as an antagonist for certain dopamine and serotonin receptors, helping manage symptoms of the disorder.

API suppliers (23)

Suppliers of Iloperidone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• HARMAN FINOCHEM LTDIndia2 active DMF GMP on record
• SWATI SPENTOSE PRIVATE LTDIndia2 active DMF
• Apex Healthcare LimitedIndia2 active DMF
• MAHENDRA CHEMICALSIndia2 active DMF
• W R GRACE AND CO -CONNUnited States2 active DMF
• MOEHS IBERICA SLSpain1 active DMF GMP on record
• CAMBREX KARLSKOGA ABSweden1 active DMF GMP on record
• Formosa Laboratories, Inc.Taiwan1 active DMF GMP on record
• Alembic Pharmaceuticals LimitedIndia1 active DMF GMP on record
• Viyash Scientific LtdIndia1 active DMF GMP on record
• PROCOS SPAItaly1 active DMF GMP on record
• Lupin LimitedIndia1 active DMF GMP on record
• SHIJIAZHUANG CANSAV PHARMACEUTICAL TECHNOLOGY CO LTDChina1 active DMF
• DELTA SYNTHETIC CO LTDTaiwan1 active DMF
• SANOFI PHARMACEUTICALS INC
• PROFARMACO SRL
• NAPP CHEMICALS INC
• KONDUSKAR LABORATORIES PVT LTD
• GUFIC BIOSCIENCES LTD GMP on record
• MYLAN LABORATORIES LTD GMP on record
• HOECHST AG
• SYN-TECH CHEM AND PHARM CO LTDTaiwan
• JENSEN-SALSBERY LABS DIV RICHARDSON-MERRILL INC

Patent & exclusivity (US)

Per the FDA Orange Book (103 approved US products), the latest listed US patent on Iloperidone expires 28 Sept 2035 and exclusivity 24 Sept 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide

Canonical SMILES

CCN(CC)CC(=O)NC1=C(C=CC=C1C)C

InChIKey

NNJVILVZKWQKPM-UHFFFAOYSA-N

Therapeutic areas