Furosemide

Overview

Furosemide is a high-ceiling diuretic of the class of sulfonamide loop diuretics, used primarily to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It functions by inhibiting the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle, thereby increasing the excretion of sodium, water, and other ions.

API suppliers (22)

Suppliers of Furosemide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• KALINTIS HEALTHCARE PVT LTDIndia1 active DMF
• SRI KRISHNA PHARMACEUTICALS LTDIndia1 active DMF GMP on record
• CURIA INDIA PRIVATE LIMITEDIndia1 active DMF
• TAPI NL BVNetherlands1 active DMF
• HALEOS LABS LTDIndia1 active DMF
• Ipca Laboratories LimitedIndia1 active DMF GMP on record
• FIS FABBRICA ITALIANA SINTETICI SPAItaly1 active DMF GMP on record
• SCHARPER SPA
• CHINOIN PHARMACEUTCIAL AND CHEMICAL WORKS CO LTD
• DINAMITE DIPHARMA SPA
• ORION CORP FARMOS CHEMICAL PLANT
• INTERMEDI CHIMICI SINTETICI SPA ZONA INDUSTRIALE
• SELOC AG
• SALSBURY CHEMICALS INC
• OLON SPAItaly GMP on record
• TRIFARMA SPAItaly GMP on record
• EUROAPI GERMANY GMBHGermanyCEP GMP on record
• MANGALAM DRUGS AND ORGANICS LTD
• HOECHST CELANESE CORP
• SOLMAG SPA
• PLANTEX LTD CHEMICAL AND PHARMACEUTICAL WORKS
• CIECH POLFA

Patent & exclusivity (US)

Per the FDA Orange Book (46 approved US products), the latest listed US patent on Furosemide expires 3 Apr 2034. Generic API sourcing typically opens up once these lapse.

Therapeutic areas