Furosemide

Overview

Furosemide is a high-ceiling diuretic of the class of sulfonamide loop diuretics, used primarily to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It functions by inhibiting the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle, thereby increasing the excretion of sodium, water, and other ions.

API suppliers (24)

Suppliers of Furosemide backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• TAPI NL BV1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• TAPI NL BV1 active DMF
• Ipca Laboratories LimitedIndia1 active DMF
• SRI KRISHNA PHARMACEUTICALS LTDIndia1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• TAPI NL BV1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• SRI KRISHNA PHARMACEUTICALS LTDIndia1 active DMF
• SELOC AG
• SALSBURY CHEMICALS INC
• TRIFARMA SPA
• INTERMEDI CHIMICI SINTETICI SPA ZONA INDUSTRIALE
• SOLMAG SPA
• MANGALAM DRUGS AND ORGANICS LTD
• ORION CORP FARMOS CHEMICAL PLANT
• HOECHST CELANESE CORP
• DINAMITE DIPHARMA SPA
• CHINOIN PHARMACEUTCIAL AND CHEMICAL WORKS CO LTD
• SCHARPER SPA
• CIECH POLFA
• PLANTEX LTD CHEMICAL AND PHARMACEUTICAL WORKS
• OLON SPAItaly

Patent & exclusivity (US)

Per the FDA Orange Book (46 approved US products), the latest listed US patent on Furosemide expires 2 Apr 2034. Generic API sourcing typically opens up once these lapse.

Therapeutic areas