Furosemide
Overview
Furosemide is a high-ceiling diuretic of the class of sulfonamide loop diuretics, used primarily to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It functions by inhibiting the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle, thereby increasing the excretion of sodium, water, and other ions.
API suppliers (22)
Suppliers of Furosemide evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 10 of 22 suppliers.
6 of 22 hold a GMP certificate on record in the EU or UK registers · 1 holds a European CEP for this substance
- Ipca Laboratories LimitedIndia1 active DMF GMP on record
- SRI KRISHNA PHARMACEUTICALS LTDIndia1 active DMF GMP on record
- FIS FABBRICA ITALIANA SINTETICI SPAItaly1 active DMF GMP on record
- CURIA INDIA PRIVATE LIMITEDIndia1 active DMF
- KALINTIS HEALTHCARE PVT LTDIndia1 active DMF
- HALEOS LABS LTDIndia1 active DMF
- TAPI NL BVNetherlands1 active DMF
- ORION CORP FARMOS CHEMICAL PLANT
- EUROAPI GERMANY GMBHGermanyCEP GMP on record
- SELOC AG
- INTERMEDI CHIMICI SINTETICI SPA ZONA INDUSTRIALE
- SALSBURY CHEMICALS INC
- TRIFARMA SPAItaly GMP on record
- OLON SPAItaly GMP on record
- MANGALAM DRUGS AND ORGANICS LTD
- SOLMAG SPA
- HOECHST CELANESE CORP
- PLANTEX LTD CHEMICAL AND PHARMACEUTICAL WORKS
- CIECH POLFA
- SCHARPER SPA
- CHINOIN PHARMACEUTCIAL AND CHEMICAL WORKS CO LTD
- DINAMITE DIPHARMA SPA
EU CEP holders (5)
Companies holding a valid EU Certificate of Suitability (CEP) for Furosemide, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.
Patent & exclusivity (US)
Per the FDA Orange Book (46 approved US products), the latest listed US patent on Furosemide expires 10 Jan 2042. Generic API sourcing typically opens up once these lapse.
Therapeutic areas
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