Exemestane

Overview

Exemestane is an oral steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in postmenopausal women. It works by decreasing the amount of estrogen produced by the body, thus slowing or stopping the growth of breast cancer cells that rely on estrogen to proliferate.

API suppliers (15)

Suppliers of Exemestane evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CURIA SPAIN SAUSpain1 active DMF GMP on record
• STERLING SPAItaly1 active DMF GMP on record
• SYMBIOTICA SPECIALITY INGREDIENTS SDN BHDMalaysia1 active DMF
• FARMABIOS SPAItaly1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• CORAL DRUGS PVT LTDIndia1 active DMF GMP on record
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• SCINOPHARM TAIWAN LTDTaiwan1 active DMF
• Cipla USA, Inc.USA1 active DMF
• PERRIGO API LTD
• Apotex Pharmachem India Pvt. Ltd.India
• DR REDDYS LABORATORIES LTD GMP on record
• TRIFARMA SPAItaly GMP on record
• MAC CHEM PRODUCTS INDIA PVT LTD GMP on record
• ZYFINE DIV CADILA HEALTHCARE LTD

Chemical identity

IUPAC name

10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione

Canonical SMILES

CC12CCC3C(C1CCC2=O)CC(=C)C4=CC(=O)C=CC34C

InChIKey

BFYIZQONLCFLEV-UHFFFAOYSA-N

Therapeutic areas