Afatinib
CAS 439081-18-2Small Molecule
Overview
Afatinib is a small molecule inhibitor targeting the ErbB family of receptors and used in the treatment of non-small cell lung cancer. It irreversibly binds to and inhibits EGFR (ErbB1) and HER2 (ErbB2) tyrosine kinases, preventing phosphorylation and activation of downstream signaling pathways.
Therapeutic areas
OncologyNon-Small Cell Lung Cancer
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