Afatinib

CAS 439081-18-2 2 FDA-DMF suppliersSmall Molecule

Overview

Afatinib is a small molecule inhibitor targeting the ErbB family of receptors and used in the treatment of non-small cell lung cancer. It irreversibly binds to and inhibits EGFR (ErbB1) and HER2 (ErbB2) tyrosine kinases, preventing phosphorylation and activation of downstream signaling pathways.

Therapeutic areas

OncologyNon-Small Cell Lung Cancer

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