Adagrasib

CAS 2389149-53-7 1 API supplierSmall Molecule

Overview

Adagrasib is a small molecule inhibitor targeting the KRAS G12C mutation, a common oncogenic driver in several types of cancer including non-small cell lung cancer (NSCLC). It works by selectively binding to and inhibiting the mutant KRAS protein, thereby inhibiting cancer cell proliferation.

API suppliers (1)

Suppliers of Adagrasib evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Adagrasib expires 21 Aug 2043 and exclusivity 12 Dec 2029. Generic API sourcing typically opens up once these lapse.

Therapeutic areas

Oncology
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