Abrocitinib

CAS 1643489-24-9 4 API suppliersSmall Molecule

Overview

Abrocitinib is an oral selective inhibitor of Janus kinase 1 (JAK1), approved for the treatment of moderate-to-severe atopic dermatitis. It works by modulating the immune response involved in the pathogenesis of the disease.

API suppliers (4)

Suppliers of Abrocitinib evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

Where these suppliers are
India1Spain1China1

Country recorded for 3 of 4 suppliers.

3 of 4 hold a GMP certificate on record in the EU or UK registers

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Abrocitinib expires 14 Jan 2036 and exclusivity 14 Jan 2027. Generic API sourcing typically opens up once these lapse.

Therapeutic areas

DermatologyRheumatologyImmunology
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