Overview

GlaxoSmithKline plc is a global healthcare company that focuses on developing and manufacturing a wide range of pharmaceutical products, vaccines, and consumer healthcare goods. The company emphasizes innovation in the fields of pharmaceuticals and vaccines, aiming to improve global health and well-being.

Therapeutic areas

API / Drug Master Files

GlaxoSmithKline plc holds 10 active (25 total) FDA Type II Drug Master Files — identifying it as an active-substance / API supplier. Type II DMFs are filed with the FDA to support the use of an active pharmaceutical ingredient in drug applications.

  • FLUTICASONE PROPIONATEActive2018-08-22
  • FLUTICASONE FUROATEActive2017-09-08
  • FLUTICASONE PROPIONATEActive2017-04-11
  • UMECLIDINIUM BROMIDEActive2012-11-29
  • VILANTEROL TRIFENATATE (GW642444)Active2012-06-19
  • ALBUTEROLActive2011-12-21
  • SALMETEROL XINAFOATEActive2011-03-23
  • CEFUROXIME SODIUMActive2011-03-01
  • CEFTAZIDIMEActive2011-03-01
  • PAROXETINE HYDROCHLORIDE HEMIHYDRATEActive2000-09-15
  • CLOBETASOL PROPIONATEInactive2012-12-20
  • AMOXICILLIN SODIUMInactive2011-02-11
  • TICARCILLIN DISODIUM BULK (STERILE )Inactive2002-07-31
  • CLAVULANATE POTASSIUM STERILE BULKInactive2002-06-13
  • HIV VACCINE (GPL 120/NEFTA/ASO2A)Inactive2001-10-04

Showing 15 of 25 Drug Master Files.

FDA compliance signals

25 FDA enforcement records linked to this company.

  • recall — Class III2024-06-12

    Labeling: Incorrect Lot and/or Expiration Date: The carton has incorrect expiration of 2026-MAY*, whereas the correct expiration date, which is on the tablet bottle label, is 2025-APR.

  • 4832024-04-19

    Complaint Handling Procedure

  • recall — Class III2024-01-03

    Failed Release Testing: Coarse Particle Mass for umeclidinium Out of Specification

  • recall — Class III2022-06-01

    Labeling: incorrect or missing lot and/or expiration date. An incorrect expiration date was printed on the product labeling with an expiration date of January 2027, whereas the correct expiration date is September 2026.

  • recall — Class II2017-05-31

    Defective Delivery System: Elevated number of units with out of specification results for leak rate

  • recall — Class II2017-04-12

    Defective Delivery System: Elevated number of units with out of specification results for leak rate.

  • recall — Class II2016-07-27

    Penicillin Cross Contamination

  • recall — Class II2016-07-27

    Penicillin Cross Contamination

  • recall — Class II2016-07-27

    Penicillin Cross Contamination

  • recall — Class II2016-07-27

    Penicillin Cross Contamination

  • 4832016-04-21

    Complaint Handling Procedure

  • 4832016-04-21

    Investigations of discrepancies, failures

  • recall — Class II2015-12-16

    Defective Delivery System: Some canisters may not contain sufficient propellant to deliver the labeled claim of 200 actuations through the end of shelf life.

  • recall — Class II2015-09-02

    Penicillin Cross Contamination and Presence of Foreign Substance. Product was contaminated with penicillin and foreign substances during manufacturing process.

  • recall — Class II2015-09-02

    Penicillin Cross Contamination and Presence of Foreign Substance. Product was contaminated with penicillin and foreign substances during manufacturing process.

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