Zuranolone

CAS 1632051-40-1Small Molecule

Overview

Zuranolone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4105630).

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Zuranolone expires 23 Aug 2037 and exclusivity 31 Oct 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
1-[2-[(3R,5R,8R,9R,10S,13S,14S,17S)-3-hydroxy-3,13-dimethyl-2,4,5,6,7,8,9,10,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl]pyrazole-4-carbonitrile
Canonical SMILES
C[C@]1(CC[C@H]2[C@@H](C1)CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4C(=O)CN5C=C(C=N5)C#N)C)O
InChIKey
HARRKNSQXBRBGZ-GVKWWOCJSA-N
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