Zongertinib

Overview

Zongertinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL5314498).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Zongertinib expires 21 Jul 2041 and exclusivity 8 Aug 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-[1-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]pyrimido[5,4-d]pyrimidin-6-yl]piperidin-4-yl]prop-2-enamide

Canonical SMILES

CC1=C(C=CC(=C1)NC2=NC=NC3=CN=C(N=C32)N4CCC(CC4)NC(=O)C=C)OC5=CC6=C(C=C5)N(C=N6)C

InChIKey

YSGNGFPNTLERCR-UHFFFAOYSA-N