Zoliflodacin

Overview

Zoliflodacin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3544978).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Zoliflodacin expires 21 Jan 2034 and exclusivity 12 Dec 2035. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]spiro[1,3-diazinane-5,8'-5,15-dioxa-2,14-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(17),10,12(16),13-tetraene]-2,4,6-trione

Canonical SMILES

C[C@@H]1CN2[C@H]([C@@H](O1)C)C3(CC4=CC5=C(C(=C42)F)ON=C5N6[C@H](COC6=O)C)C(=O)NC(=O)NC3=O

InChIKey

ZSWMIFNWDQEXDT-ZESJGQACSA-N