Zidesamtinib
CAS 2739829-00-4Small Molecule
Overview
Zidesamtinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL5314497).
Patent & exclusivity (US)
Per the FDA Orange Book (2 approved US products), the latest listed US patent on Zidesamtinib expires 30 Sept 2042 and exclusivity 22 Jul 2031. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (19R)-3-ethyl-16-fluoro-10,19-dimethyl-20-oxa-3,4,9,10,11,23-hexazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine
- Canonical SMILES
- CCN1C2=C(CC3=NN(N=C3C4=C(C=C(C=C4)F)[C@H](OC5=C(N=CC2=C5)N)C)C)C=N1
- InChIKey
- DTWUUAFTYSMNQX-GFCCVEGCSA-N
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