Zavegepant

Overview

Zavegepant is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2397415).

API suppliers (1)

Suppliers of Zavegepant backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MOEHS IBERICA SLSpain1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Zavegepant expires 26 Jun 2034 and exclusivity 9 Mar 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide

Canonical SMILES

CC1=CC(=CC2=C1NN=C2)C[C@H](C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O

InChIKey

JJVAPHYEOZSKJZ-JGCGQSQUSA-N