Vorasidenib

Overview

Vorasidenib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4279047).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Vorasidenib expires 16 Jan 2039 and exclusivity 6 Aug 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-(6-chloro-2-pyridinyl)-2-N,4-N-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine

Canonical SMILES

C[C@H](C(F)(F)F)NC1=NC(=NC(=N1)C2=NC(=CC=C2)Cl)N[C@H](C)C(F)(F)F

InChIKey

QCZAWDGAVJMPTA-RNFRBKRXSA-N