Vibegron

Overview

Vibegron is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2107826).

API suppliers (9)

Suppliers of Vibegron evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• CHANGZHOU PHARMACEUTICAL FACTORYChina1 active DMF GMP on record
• AMI LIFESCIENCES PRIVATE LTDIndia1 active DMF GMP on record
• Yangzhou Aurisco Pharmaceutical Co.,Ltd.China1 active DMF
• Porton Pharma Solutions Ltd.China1 active DMF
• MSN Organics Private LimitedIndia1 active DMF
• HONOUR LAB LTDIndia1 active DMF GMP on record
• LEE PHARMA LTDIndia1 active DMF GMP on record
• ALIVUS LIFE SCIENCES LTDIndia1 active DMF GMP on record
• Zhejiang Jingsheng Pharmaceutical Co., Ltd.China1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Vibegron expires 6 Jul 2042 and exclusivity 18 Dec 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(6S)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-4-oxo-7,8-dihydro-6H-pyrrolo[1,2-a]pyrimidine-6-carboxamide

Canonical SMILES

C1C[C@@H](N[C@@H]1CC2=CC=C(C=C2)NC(=O)[C@@H]3CCC4=NC=CC(=O)N34)[C@@H](C5=CC=CC=C5)O

InChIKey

DJXRIQMCROIRCZ-XOEOCAAJSA-N