Vandetanib

Overview

Vandetanib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL24828).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Vandetanib expires 8 Aug 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine

Canonical SMILES

CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

InChIKey

UHTHHESEBZOYNR-UHFFFAOYSA-N