Vamorolone

Overview

Vamorolone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2348780).

API suppliers (1)

Suppliers of Vamorolone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• YANGZHOU LIANAO BIOPHARMACEUTICAL CO LTD1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Vamorolone expires 16 Jul 2040 and exclusivity 26 Oct 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one

Canonical SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CO)O)C)C

InChIKey

ZYTXTXAMMDTYDQ-DGEXFFLYSA-N