Valbenazine

CAS 1025504-45-3Small Molecule

Overview

Valbenazine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2364639).

Patent & exclusivity (US)

Per the FDA Orange Book (8 approved US products), the latest listed US patent on Valbenazine expires 10 Aug 2040 and exclusivity 18 Aug 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
[(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate
Canonical SMILES
CC(C)C[C@@H]1CN2CCC3=CC(=C(C=C3[C@H]2C[C@H]1OC(=O)[C@H](C(C)C)N)OC)OC
InChIKey
GEJDGVNQKABXKG-CFKGEZKQSA-N
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