Trofinetide

CAS 853400-76-7 3 FDA-DMF suppliersSmall Molecule

Overview

Trofinetide is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL197084).

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Trofinetide expires 12 Jan 2043 and exclusivity 9 Sept 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
(2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid
Canonical SMILES
C[C@]1(CCCN1C(=O)CN)C(=O)N[C@@H](CCC(=O)O)C(=O)O
InChIKey
BUSXWGRAOZQTEY-SDBXPKJASA-N

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