Trilaciclib

Overview

Trilaciclib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3894860).

API suppliers (2)

Suppliers of Trilaciclib backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Hetero Labs LimitedIndia1 active DMF
• TAPI NL BVNetherlands1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Trilaciclib expires 13 Nov 2040 and exclusivity 12 Feb 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[[5-(4-methylpiperazin-1-yl)-2-pyridinyl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1'-cyclohexane]-10-one

Canonical SMILES

CN1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6

InChIKey

PDGKHKMBHVFCMG-UHFFFAOYSA-N