Trilaciclib
Overview
Trilaciclib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3894860).
API suppliers (2)
Suppliers of Trilaciclib evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
1 of 2 holds a GMP certificate on record in the EU or UK registers
- TAPI NL BVNetherlands1 active DMF
- Hetero Labs LimitedIndia1 active DMF GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Trilaciclib expires 13 Nov 2040 and exclusivity 12 Feb 2026. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 4-[[5-(4-methylpiperazin-1-yl)-2-pyridinyl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1'-cyclohexane]-10-one
- Canonical SMILES
- CN1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6
- InChIKey
- PDGKHKMBHVFCMG-UHFFFAOYSA-N
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