Tradipitant

Overview

Tradipitant is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3544984).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Tradipitant expires 9 Aug 2036 and exclusivity 30 Dec 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-pyridin-4-yltriazol-4-yl]-3-pyridinyl]-(2-chlorophenyl)methanone

Canonical SMILES

C1=CC=C(C(=C1)C(=O)C2=C(N=CC=C2)C3=C(N(N=N3)CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=CC=NC=C5)Cl

InChIKey

CAVRKWRKTNINFF-UHFFFAOYSA-N