Tovorafenib
CAS 1096708-71-2Small Molecule
Overview
Tovorafenib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3348923).
Patent & exclusivity (US)
Per the FDA Orange Book (2 approved US products), the latest listed US patent on Tovorafenib expires 23 Jun 2035 and exclusivity 23 Apr 2031. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide
- Canonical SMILES
- C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
- InChIKey
- VWMJHAFYPMOMGF-ZCFIWIBFSA-N
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