Tobramycin

Overview

Tobramycin is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1747).

API suppliers (13)

Suppliers of Tobramycin backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• LIVZON GROUP FUZHOU FUXING PHARMACEUTICAL CO LTD2 active DMF
• Xellia Pharmaceuticals ApSDenmark2 active DMF
• CHONGQING CARELIFE PHARMACEUTICAL CO LTDChina1 active DMF
• TAPI NL BV1 active DMF
• CHONGQING CARELIFE PHARMACEUTICAL CO LTDChina1 active DMF
• TAPI NL BV1 active DMF
• TAPI NL BV1 active DMF
• GUANGDONG QINGYUAN NEW NORTH RIVER PHARMACEUTICAL CO LTD
• LILLY RESEARCH LABORATORIES
• PHARMACHIM ECONOMIC CORP
• Zhejiang Hisun Pharmaceutical Co., Ltd.China
• Kangmei Pharmaceutical Co., Ltd.China
• ALPHARMA APS

Patent & exclusivity (US)

Per the FDA Orange Book (38 approved US products), the latest listed US patent on Tobramycin expires 4 Nov 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol

Canonical SMILES

C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N

InChIKey

NLVFBUXFDBBNBW-PBSUHMDJSA-N