Tizanidine

Overview

Tizanidine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1079).

API suppliers (11)

Suppliers of Tizanidine evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• DR REDDYS LABORATORIES LTD2 active DMF GMP on record
• MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
• Zydus Lifesciences LimitedIndia1 active DMF GMP on record
• PH HEALTH LTD1 active DMF
• Viyash Scientific LtdIndia1 active DMF GMP on record
• SNJ LIFECARE PVT LTDIndia1 active DMF
• FARMAK ASUkraine1 active DMF
• Sun Pharmaceutical Industries LimitedIndia1 active DMF GMP on record
• Unichem Laboratories Ltd.India1 active DMF GMP on record
• TAPI NL BVNetherlands1 active DMF
• Apotex Pharmachem India Pvt. Ltd.India

Patent & exclusivity (US)

Per the FDA Orange Book (55 approved US products), the latest listed US patent on Tizanidine expires 7 May 2042. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine

Canonical SMILES

C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl

InChIKey

XFYDIVBRZNQMJC-UHFFFAOYSA-N