Tepotinib

Overview

Tepotinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3402762).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Tepotinib expires 19 Mar 2030 and exclusivity 3 Feb 2028. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

3-[1-[[3-[5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl]phenyl]methyl]-6-oxopyridazin-3-yl]benzonitrile

Canonical SMILES

CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N

InChIKey

AHYMHWXQRWRBKT-UHFFFAOYSA-N