Tapinarof
Overview
Tapinarof is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL259571).
API suppliers (7)
Suppliers of Tapinarof evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
3 of 7 hold a GMP certificate on record in the EU or UK registers
- MAITHRI DRUGS PRIVATE LTDIndia1 active DMF GMP on record
- MSN Organics Private LimitedIndia1 active DMF
- MATRIX PHARMACORP PRIVATE LTDIndia1 active DMF
- METROCHEM API PRIVATE LTDIndia1 active DMF
- Taro Pharmaceutical Industries Ltd.Israel1 active DMF GMP on record
- TAPI NL BVNetherlands1 active DMF
- Emcure Pharmaceuticals LimitedIndia1 active DMF GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Tapinarof expires 18 Dec 2039 and exclusivity 12 Dec 2027. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 5-[(E)-2-phenylethenyl]-2-propan-2-ylbenzene-1,3-diol
- Canonical SMILES
- CC(C)C1=C(C=C(C=C1O)/C=C/C2=CC=CC=C2)O
- InChIKey
- ZISJNXNHJRQYJO-CMDGGOBGSA-N
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