Talazoparib
CAS 1207456-01-6Small Molecule
Overview
Talazoparib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3137320).
Patent & exclusivity (US)
Per the FDA Orange Book (6 approved US products), the latest listed US patent on Talazoparib expires 20 Oct 2031 and exclusivity 20 Jun 2026. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (11S,12R)-7-fluoro-11-(4-fluorophenyl)-12-(2-methyl-1,2,4-triazol-3-yl)-2,3,10-triazatricyclo[7.3.1.05,13]trideca-1,5(13),6,8-tetraen-4-one
- Canonical SMILES
- CN1C(=NC=N1)[C@@H]2[C@H](NC3=CC(=CC4=C3C2=NNC4=O)F)C5=CC=C(C=C5)F
- InChIKey
- HWGQMRYQVZSGDQ-HZPDHXFCSA-N
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