Tafluprost

Overview

Tafluprost is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1963683).

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Tafluprost expires 27 May 2029. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate

Canonical SMILES

CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/C(COC2=CC=CC=C2)(F)F)O)O

InChIKey

WSNODXPBBALQOF-VEJSHDCNSA-N