Tafenoquine

CAS 106635-80-7Small Molecule

Overview

Tafenoquine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL298470).

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Tafenoquine expires 2 Dec 2035. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
4-N-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine
Canonical SMILES
CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC
InChIKey
LBHLFPGPEGDCJG-UHFFFAOYSA-N
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