Suzetrigine

Overview

Suzetrigine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL5314487).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Suzetrigine expires 4 Dec 2040 and exclusivity 30 Jan 2030. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide

Canonical SMILES

C[C@H]1[C@H]([C@@H](O[C@@]1(C)C(F)(F)F)C(=O)NC2=CC(=NC=C2)C(=O)N)C3=C(C(=C(C=C3)F)F)OC

InChIKey

XSQUJFKRXZMOKA-PAFIKIDNSA-N