Sparsentan

Overview

Sparsentan is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL539423).

API suppliers (1)

Suppliers of Sparsentan evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Sparsentan expires 29 Mar 2030 and exclusivity 5 Sept 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide

Canonical SMILES

CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC

InChIKey

WRFHGDPIDHPWIQ-UHFFFAOYSA-N