Sonidegib

Overview

Sonidegib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2105737).

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Sonidegib expires 30 Mar 2036. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

N-[6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-3-pyridinyl]-2-methyl-3-[4-(trifluoromethoxy)phenyl]benzamide

Canonical SMILES

C[C@@H]1CN(C[C@@H](O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F

InChIKey

VZZJRYRQSPEMTK-CALCHBBNSA-N