Siponimod

Overview

Siponimod is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2336071).

API suppliers (1)

Suppliers of Siponimod backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Sichuan Kelun Pharmaceutical Co., Ltd.China1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Siponimod expires 23 Apr 2036. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid

Canonical SMILES

CCC1=C(C=CC(=C1)/C(=N/OCC2=CC(=C(C=C2)C3CCCCC3)C(F)(F)F)/C)CN4CC(C4)C(=O)O

InChIKey

KIHYPELVXPAIDH-HNSNBQBZSA-N