Siponimod
CAS 1230487-00-9 1 API supplierSmall Molecule
Overview
Siponimod is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL2336071).
API suppliers (1)
Suppliers of Siponimod evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Where these suppliers are
China1
- Sichuan Kelun Pharmaceutical Co., Ltd.China1 active DMF
Patent & exclusivity (US)
Per the FDA Orange Book (3 approved US products), the latest listed US patent on Siponimod expires 23 Apr 2036. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid
- Canonical SMILES
- CCC1=C(C=CC(=C1)/C(=N/OCC2=CC(=C(C=C2)C3CCCCC3)C(F)(F)F)/C)CN4CC(C4)C(=O)O
- InChIKey
- KIHYPELVXPAIDH-HNSNBQBZSA-N
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