Sevabertinib
CAS 2521285-05-0Small Molecule
Overview
Sevabertinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL6068074).
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Sevabertinib expires 14 Nov 2043 and exclusivity 19 Nov 2030. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 3-(3-chloro-2-methoxyanilino)-2-[3-[[(2S)-1,4-dioxan-2-yl]methoxy]-4-pyridinyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
- Canonical SMILES
- COC1=C(C=CC=C1Cl)NC2=C(NC3=C2C(=O)NCC3)C4=C(C=NC=C4)OC[C@@H]5COCCO5
- InChIKey
- VYQVHWNNPKOJEA-AWEZNQCLSA-N
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