Selumetinib

CAS 606143-52-6Small Molecule

Overview

Selumetinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1614701).

Patent & exclusivity (US)

Per the FDA Orange Book (4 approved US products), the latest listed US patent on Selumetinib expires 26 Mar 2029 and exclusivity 19 Nov 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name
6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
Canonical SMILES
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
InChIKey
CYOHGALHFOKKQC-UHFFFAOYSA-N
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