Selpercatinib

Overview

Selpercatinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4559134).

API suppliers (1)

Suppliers of Selpercatinib backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MSN Laboratories Private LimitedIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (6 approved US products), the latest listed US patent on Selpercatinib expires 10 Apr 2039 and exclusivity 29 Nov 2031. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

6-(2-hydroxy-2-methylpropoxy)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile

Canonical SMILES

CC(C)(COC1=CN2C(=C(C=N2)C#N)C(=C1)C3=CN=C(C=C3)N4CC5CC(C4)N5CC6=CN=C(C=C6)OC)O

InChIKey

XIIOFHFUYBLOLW-UHFFFAOYSA-N