Rocuronium

Overview

Rocuronium is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL1201244).

API suppliers (9)

Suppliers of Rocuronium evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• FARMHISPANIA SASpain2 active DMF
• Mankind Pharma LimitedIndia1 active DMF GMP on record
• GLAND PHARMA LTDIndia1 active DMF GMP on record
• Gland Chemicals Private LimitedIndia1 active DMF
• ZHEJIANG XIANJU PHARMACEUTICAL CO LTD1 active DMF
• Zhejiang Huahai Pharmaceutical Co., Ltd.China1 active DMF GMP on record
• SHANGHAI NEUTAN PHARMACEUTICAL CO LTD1 active DMF
• SHANGHAI JUNMED HEALTHCARE CO LTDChina1 active DMF
• Reliance Life Sciences Pvt. Ltd.India GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (36 approved US products), the latest listed US patent on Rocuronium expires 22 Jul 2039. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate

Canonical SMILES

CC(=O)O[C@H]1[C@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C

InChIKey

YXRDKMPIGHSVRX-OOJCLDBCSA-N