Rilpivirine

Overview

Rilpivirine is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL175691).

API suppliers (2)

Suppliers of Rilpivirine backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• MSN PHARMACHEM PRIVATE LTD2 active DMF
• Janssen Pharmaceutica NVBelgium1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (3 approved US products), the latest listed US patent on Rilpivirine expires 22 Oct 2037 and exclusivity 14 Sept 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile

Canonical SMILES

CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N

InChIKey

YIBOMRUWOWDFLG-ONEGZZNKSA-N