Remdesivir

Overview

Remdesivir is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4065616).

API suppliers (2)

Suppliers of Remdesivir evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• MSN LIFE SCIENCES PRIVATE LIMITEDIndia1 active DMF GMP on record
• HONOUR LAB LTDIndia1 active DMF GMP on record

Patent & exclusivity (US)

Per the FDA Orange Book (1 approved US product), the latest listed US patent on Remdesivir expires 28 Nov 2041 and exclusivity 13 Jan 2027. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate

Canonical SMILES

CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

InChIKey

RWWYLEGWBNMMLJ-YSOARWBDSA-N