Progesterone

Overview

Progesterone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL103).

API suppliers (16)

Suppliers of Progesterone evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.

• PHARMACIA AND UPJOHN CO LLC WHOLLY OWNED SUB OF PFIZER INC2 active DMF
• SYMBIOTEC PHARMALAB LTD1 active DMF GMP on record
• Zhejiang Shenzhou Pharmaceutical Co., Ltd.China1 active DMF
• ZHEJIANG XIANJU PHARMACEUTICAL CO LTD1 active DMF
• JIANGXI HONGYUAN PHARMACEUTICAL CO LTD1 active DMF
• INDUSTRIALE CHIMICA SRLItaly1 active DMF GMP on record
• FIS FABBRICA ITALIANA SINTETICI SPAItaly1 active DMF GMP on record
• ASPEN OSS BVNetherlands1 active DMF GMP on record
• JIANGSU JIAERKE PHARMACEUTICALS GROUP CORP LTDChina1 active DMF
• Hubei Gedian Humanwell Pharmaceutical Co. LtdChina1 active DMF GMP on record
• SIGNA SA DE CV
• SIGMA F AND D DIV LTD
• CINBERG B L MD
• PRODUCTOS QUIMICOS NATURALES SA DE CV
• CHANGZHOU JIAERKE PHARMACEUTICALS GROUP CORP LTD
• ORGANON SUB AKZONA INC

EU CEP holders (5)

Companies holding a valid EU Certificate of Suitability (CEP) for Progesterone, from the EDQM certification database. A CEP holder is a documented EU-market source of the substance — not necessarily the manufacturer — and these are not yet profiled in our directory.

Patent & exclusivity (US)

Per the FDA Orange Book (23 approved US products), the latest listed US patent on Progesterone expires — and exclusivity 22 Mar 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Canonical SMILES

CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

InChIKey

RJKFOVLPORLFTN-LEKSSAKUSA-N