Progesterone

Overview

Progesterone is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL103).

API suppliers (13)

Suppliers of Progesterone backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• PHARMACIA AND UPJOHN CO WHOLLY OWNED SUB PFIZER INC2 active DMF
• Zhejiang Hisun Pharmaceutical Co., Ltd.China2 active DMF
• ASPEN OSS BV1 active DMF
• ASPEN OSS BV1 active DMF
• ASPEN OSS BV1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• FIS FABBRICA ITALIANA SINTETICI SPA1 active DMF
• CHANGZHOU JIAERKE PHARMACEUTICALS GROUP CORP LTD
• PRODUCTOS QUIMICOS NATURALES SA DE CV
• SIGNA SA DE CV
• CINBERG B L MD
• SIGMA F AND D DIV LTD
• ORGANON SUB AKZONA INC

Patent & exclusivity (US)

Per the FDA Orange Book (22 approved US products), the latest listed US patent on Progesterone expires — and exclusivity 22 Mar 2026. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Canonical SMILES

CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

InChIKey

RJKFOVLPORLFTN-LEKSSAKUSA-N