Pretomanid
Overview
Pretomanid is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL227875).
API suppliers (2)
Suppliers of Pretomanid evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
Country recorded for 1 of 2 suppliers.
- SHENYANG HONGQI PHARMACEUTICAL CO LTD1 active DMF
- TIANISH LABORATORIES PRIVATE LTDIndia1 active DMF
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Pretomanid expires — and exclusivity 14 Aug 2031. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- (6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
- Canonical SMILES
- C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
- InChIKey
- ZLHZLMOSPGACSZ-NSHDSACASA-N
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