Pirtobrutinib

Overview

Pirtobrutinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4650485).

API suppliers (2)

Suppliers of Pirtobrutinib backed by a verifiable FDA Type II Drug Master File. Source: FDA quarterly DMF list.

• Dr. Reddy's Laboratories Ltd.India1 active DMF
• MSN Laboratories Private LimitedIndia1 active DMF

Patent & exclusivity (US)

Per the FDA Orange Book (2 approved US products), the latest listed US patent on Pirtobrutinib expires 14 Sept 2041 and exclusivity 3 Dec 2032. Generic API sourcing typically opens up once these lapse.

Chemical identity

IUPAC name

5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide

Canonical SMILES

C[C@@H](C(F)(F)F)N1C(=C(C(=N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC(=C3)F)OC)C(=O)N)N

InChIKey

FWZAWAUZXYCBKZ-NSHDSACASA-N