Pexidartinib
CAS 1029044-16-3Small Molecule
Overview
Pexidartinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL3813873).
Patent & exclusivity (US)
Per the FDA Orange Book (1 approved US product), the latest listed US patent on Pexidartinib expires 24 Jul 2038 and exclusivity 2 Aug 2026. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyridin-2-amine
- Canonical SMILES
- C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F
- InChIKey
- JGWRKYUXBBNENE-UHFFFAOYSA-N
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