Pemigatinib
Overview
Pemigatinib is a small molecule active pharmaceutical ingredient (ChEMBL CHEMBL4297522).
API suppliers (1)
Suppliers of Pemigatinib evidenced by a US FDA Type II Drug Master File or an EU Certificate of Suitability (CEP). Sources: FDA DMF list, EDQM certification database.
1 of 1 holds a GMP certificate on record in the EU or UK registers
- MSN Laboratories Private LimitedIndia1 active DMF GMP on record
Patent & exclusivity (US)
Per the FDA Orange Book (3 approved US products), the latest listed US patent on Pemigatinib expires 3 Oct 2040 and exclusivity 26 Aug 2029. Generic API sourcing typically opens up once these lapse.
Chemical identity
- IUPAC name
- 11-(2,6-difluoro-3,5-dimethoxyphenyl)-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.02,6]trideca-1,3,6,8-tetraen-12-one
- Canonical SMILES
- CCN1C2=C3C=C(NC3=NC=C2CN(C1=O)C4=C(C(=CC(=C4F)OC)OC)F)CN5CCOCC5
- InChIKey
- HCDMJFOHIXMBOV-UHFFFAOYSA-N
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